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Bioorganic and Medicinal Chemistry (B.Sc Chemistry)

Carbohydrates, amino acids, proteins, nucleic acids, enzymes, lipids and basics of drug design.

6 MonthsDuration 5Chapters32Topics
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Syllabus · पाठ्यक्रम

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01Unit 1: Carbohydrates 7 topics
  1. Classification of carbohydrates
  2. Open-chain and ring structures of glucose and fructose
  3. Mutarotation, anomers and epimers
  4. Osazone formation
  5. Killiani-Fischer synthesis and Ruff degradation
  6. Sucrose, maltose and lactose
  7. Starch and cellulose
02Unit 2: Amino Acids, Peptides and Proteins 6 topics
  1. Classification of amino acids
  2. Zwitterion and isoelectric point
  3. Strecker synthesis
  4. Peptide bond and peptide synthesis
  5. Primary, secondary, tertiary and quaternary structure
  6. Denaturation of proteins
03Unit 3: Enzymes and Lipids 7 topics
  1. Enzyme classification and nomenclature
  2. Lock-and-key and induced-fit models
  3. Factors affecting enzyme activity
  4. Michaelis-Menten equation
  5. Enzyme inhibition
  6. Fats, oils and phospholipids
  7. Saponification and iodine values
04Unit 4: Nucleic Acids 6 topics
  1. Nucleosides and nucleotides
  2. Watson-Crick model of DNA
  3. Base pairing and Chargaff's rules
  4. Types of RNA
  5. Replication, transcription and translation (outline)
  6. Genetic code
05Unit 5: Medicinal Chemistry 6 topics
  1. Classification of drugs
  2. Drug design, pharmacophore and SAR (basics)
  3. Analgesics: aspirin, paracetamol, ibuprofen
  4. Sulpha drugs and antibiotics
  5. Antimalarials: chloroquine
  6. Drug safety and side effects

About

You will be able to

  • Draw open-chain and cyclic structures of glucose and fructose and explain mutarotation
  • Explain amino acid properties, peptide bonds and levels of protein structure
  • Describe enzyme action, Michaelis-Menten kinetics and inhibition
  • Describe the structure of DNA and RNA and the flow of genetic information
  • Explain basic drug design and the synthesis and use of common drugs

Who it is for

  • B.Sc Chemistry students of Semester 2 (UP State Universities, NEP 2020)
  • Students preparing for end-semester theory papers of Chemistry

What you need

  • Fundamentals of Chemistry (Semester 1)

Questions

Which syllabus does this subject follow?

It follows the B.Sc Chemistry Semester 2 syllabus of the UP State Universities (NEP 2020 common minimum syllabus). Where your own university's syllabus differs, the centre follows your university syllabus.

How are students assessed at the centre?

Through unit-wise multiple-choice tests, a final test paper and doubt-clearing sessions that follow the university examination pattern.

Will this help in the semester examination?

Yes. Units are taught in the university order with solved numericals and exam-pattern questions.

Download the syllabus (PDF)

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